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Fairly scientific footnote, this is roughly a guide.

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In a study of thyroidectomized rats (rats whose thyroid glands had been surgically removed) treated with levothyroxine alone, no single dose was able to restore normal concentrations of TSH, T4, and T3 in the blood and normalize T4 and T3 levels in all tissues and organs analyzed ( Morreale HF et al 1995). In most tissues, the dose of levothyroxine required to produce normal T3 levels resulted in significantly elevated T4 levels.


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